All posts by : Admin

Wednesday, March 23, 2011

By causing the mutation of one specific gene, researchers have produced mice with two frequently encountered behavioral traits of persons diagnosed with autism. Autism commonly affects the ability to interact socially and is associated with repetitive behavior. The finding was reported in the March 20 online edition of Nature.

Using mice, researchers at the Massachusetts Institute of Technology (MIT) and Duke University mutated one of the genes associated with autism, known as shank3, a gene that controls the production of the shank3 protein present in the brain. Mice that were given this mutation exhibited repetitive behavior and avoided social interactions with the mice around them.

According to MIT Professor Guoping Feng: “Our study demonstrated that Shank3 mutation in mice lead to defects in neuron-neuron communications.”

Shank3 protein are found in synapses within the brain. Synapses allow brain cells (called neurons) to communicate with each other. The mutation in the mouse gene interfered with this communication, apparently producing the subsequent autism-like traits. Researchers believe their work demonstrates the important role of shank3 in the functioning of brain circuits that determine behavior.

While hundreds of genes have been linked to autism in human patients, only a small percentage have been linked to shank3. Professor Feng hypothesizes that disruptions of other genes that act on the production of brain proteins affecting synaptic communication may also be related to autistic behavior. If this disruption is real, Feng claims that treatments could be developed to correct synaptic function for any defective synaptic protein in an autistic patient.

Feng continued; “These findings and the mouse model now allow us to figure out the precise neural circuit defects responsible for these abnormal behaviours, which could lead to novel strategies and targets for developing treatment.”

About one in 110 children in the U.S., and at least one in 100 in UK, have been diagnosed with an autism spectrum disorder, for which there is currently no effective cure.

Friday, June 17, 2011

Anthony Weiner announced his resignation yesterday afternoon as a Democratic representative from New York to the U.S. House of Representatives, a position he has filled for twelve years. He has been under pressure from politicians within his own party after a sex scandal engulfed his life and that of the Democratic party.

Weiner told reporters it was “impossible” to continue in his role after the events of the last few weeks, including revelations that he was involved in sexual relationships with a number of young women over the internet, including sending lewd photos of himself, and then lying about his actions to reporters.

He announced his resignation at a press conference in a Brooklyn senior center where 20 years ago he began his political career and apologized for his “personal mistakes”. His wife, Huma Abedin, did not accompany him, but Weiner apologized to her in his speech, saying that he hopes “most importantly, that my wife and I can continue to heal from the damage that I’ve caused.” He took no questions from reporters.

On June 6, Weiner had admitted to corresponding with women he met on the internet, including exchanging lewd photos. But on June 11 he declared in an emotional interview he would not resign. Under pressure from Democrats, Weiner requested a two-week leave of absence from his position in order to obtain treatment to become “a better husband and healthier person.”

However, Democratic politicians became increasingly anxious to put the growing scandal behind them, as it distracted members from more important issues such as problems with Medicare and the need for more jobs. As the scandal gained momentum, a variety of politicians, including Nancy Pelosi, the House Minority Leader, called on him to resign. President Barack Obama said he would resign if he were in Weiner’s place in an interview with ABC News.

“Weiner exercised poor judgment in his actions and poor judgment in his reaction to the revelations,” Pelosi said in a statement after Weiner announced his resignation. “Today, he made the right judgment in resigning.”

The scandal came to light May 27 after Weiner accidentally sent a photograph of his crotch on his public stream on the social networking website Twitter, and then tried to cover it up by blaming hackers for posting the picture, denying all responsibility.

Weiner later admitted sending online messages to other women, including to a 17-year-old high school student in Delaware, though a police investigation uncovered nothing illegal. On Wednesday, a former porn actress revealed that she had engaged in an online relationship with Weiner and that Weiner had asked her to lie about the nature of their contact.

More photos have continued to emerge, including one showing his nude genitals, and others showing him half naked. On Wednesday, the National Enquirer published images of Weiner cross-dressing while he was a college student at the State University of New York at Plattsburgh. In one photo, he is seen wearing a bra and pantyhose, while in another he is oiled and wearing swimming trunks.

Colleagues said Weiner wanted to wait for the return home of his wife, Abedin, before making a final career decision. He has been married for almost a year to Abedin, who is pregnant with the couple’s first child. She is a top aide to Hillary Clinton, the Secretary of State, and the couple’s wedding was presided over by former President Bill Clinton. She returned home to Washington, D.C. on Wednesday morning after having traveled with Clinton in the Middle East and Africa since June 8.

Weiner’s district covers parts of Brooklyn and Queens, boroughs of New York City. He ran an unsuccessful campaign for mayor of New York City in 2005, and he was considered a potential candidate for future races. Known to be an outspoken supporter of liberal causes, he has irked conservatives and Democratic leaders. In 2009, he pushed for government-run health care, even though Obama had opposed the idea.

Friday, January 20, 2006

US stocks suffered their biggest declines in more than two years on concerns about oil supplies from Iran and Nigeria. Crude oil prices jumped to more than $68 a barrel, levels not seen since September last year. Gold hit a 25 year peak and last traded at $553.50 an ounce.

The Dow Jones Industrial Average (DJIA) slumped 213+ points today amid fears of Iran and terrorism. The index has now given up all its gains since the beginning of the year. Among its 30 components, only McDonalds ended the day in positive territory. Disappointing earnings dragged down shares of General Electric Co. and Citigroup Inc.

Since the start of the Q4 earnings season, many analysts have been reducing their earnings expectations. S&P 500 companies are now expected to report a profit growth of 12.7 percent, compared with earlier expectations of 15.5 percent. This analysis was done by Bloomberg using data from Thomson. Earnings growth is expected to slow down to 9.9 percent in the first quarter of this year.

Shares of GE gave up $1.35 to end at $33.33 after the firm reported its smallest earnings gain since 2004. GE is the world’s second largest firm by market value. Q4 earnings rose to 55 cents a share from 54 cents while revenue rose 2.6 percent to $40.7 billion, below analysts’ estimates.

The DJIA was dragged down by Citigroup, largest bank in US. Its stock fell $1.98 to $45.96. The company reported fourth-quarter earnings of $4.97 billion, or 98 cents a share. The earnings were below consensus estimates of $1.

Monday, September 22, 2008

Several mainstream news outlets have misstated and overstated a possible link between cellular phone use and decreased fertility in men. A single experiment, which has not yet been published in any peer reviewed journal or replicated by other scientists, observed an average decrease in sperm motility and an increase in free radicals among laboratory sperm samples that were exposed to radiation similar to the radiation produced by cellular phone use.

Dr. Ashok Agarwal of the Cleveland Clinic estimates the overall health impact of cellular phones as “very safe” and reassured a Cable News Network reporter that the research was too premature to advise lifestyle changes for the public. “Our study has not provided proof that you should stop putting cell phones in your pocket. There are many things that need to be proven before we get to that stage.” He noted that his own cell phone was in his trouser pocket while he was giving the interview. Dr. Agarwal is the lead researcher for the study and Director of the Center for Reproductive Medicine at the Cleveland Clinic.

Cell phone industry spokesman Joe Farren agreed with Dr. Agarwal’s assessment about the devices’ overall safety: “The weight of the published scientific evidence, in addition to the opinion of global health organizations, shows that there is no link between wireless usage and adverse health effects.”

The controlled experiment used sperm samples from thirty-two donors: twenty-three healthy men and nine men who had fertility problems. Sperm were then exposed to radiation for one hour at 850 megahertz, the most common frequency for cell phones in the United States. Dr. Agarwal’s study raises a possible concern that cell phones kept on belts or trouser pockets and used in conjunction with wireless bluetooth earpieces “could cause harmful effects due to the proximity of the phones and the exposure that they are causing to the gonads.” He also noted that follow-up research is needed to determine whether the body’s skin and other tissue affords protection from the potential damage.

Several news sources ran misleading reports that overstated the risk.

The Los Angeles Times asserted a fallacious causal relationship that Dr. Agarwhal had not drawn and ignored his opinions that cellular phones are safe and no change in phone use is necessary. Instead, the piece opened by ordering men to stop keeping cell phones in their pockets:

“Attention male cellphone users of reproductive age: Take that phone out of your pocket. Information published today suggests that the radio-frequency energy released by cellphones decreases sperm quality in men.”

Ciol News ran a similar account:

“Beware men! Do you have the habit of keeping your mobile phone in the pockets of your trousers while talking on hand-free? Or do clip the mobile to your belt while talking? If so you are doing that at the cost of your fertility, warns a recent study.”

Mobile Magazine went a step further, also alluding to previous media exaggerations about cellular phone dangers:

“Oh no! It seems that mobile phones are getting even more problematic than ever. After getting linked to everything from migraines to cancer, it seems that the radiation from cell phones is now being connected to stupid sperm. Yes, I’m talking about the little swimmers that lead into a conversation about the birds and the bees.”

Mobile Magazine also ended in a misleading manner with “I wonder if it’s healthier to put your phone in your shirt pocket instead,” failing to mention that Dr. Agarwal had addressed that concern and had called it an unnecessary precaution.

Not all news sources overplayed the findings. CNN and United Press International ran balanced reports that did not suggest dangers or precautions beyond the lead researcher’s conclusions.

Saturday, March 4, 2006

Buffalo, New York —The Common Council requested on Tuesday that a picture be found on what many thought was the site of a previous hotel.

The Proposed Elmwood Village Hotel would be placed on the intersection of Elmwood and Forest. It was suspected by residents and business owners in the area that hotel once stood in the same spot.

The Elmwood Village hotel is a proposed development by Savarino Construction Services Corp. In order for the project to proceed, at least five buildings (1119-1121 Elmwood) would need to be demolished. All five houses are currently occupied by businesses and residents.

After some research, a freelance journalist writing for Wikinews was able to determine that there was never a hotel on the proposed Elmwood Village Hotel site. However; there was a temporary hotel located on the northeast corner of Elmwood and Forest.

Buffalo was the host of the Pan-American Exposition from May 1 until November 2, 1901. It was a fair designed to feature the latest in technology, including electricity. There was a midway, athletic events, and had African, Eskimo, and Mexican villages. However; what is likely the most famous event that took place at the exposition was the assassination of then President William McKinley on September 6, 1901. He was shot by Leon Czolgosz just outside the Temple of Music and died eight days later while in the home of John Milburn on Delaware Avenue in Buffalo. Just a short time later, Theodore Roosevelt was inaugurated on September 14, 1901 at the Wilcox House on Delaware Avenue in Buffalo. Nearly eight million people attended the exposition.

During that time several hotels and rooming houses were built around the exposition including The Elmwood at 717 Elmwood, the Hotel Elmhurst at Forest and Lincoln Parkway, Hotel Gibbs 1005-1021 Elmwood, the R. Palmerton Merritt at 441 Forest and The Norman at 422 Forest. None of these hotels or rooming houses exist today.

Probably the most famous hotel that was built during the exposition was the Statler’s Pan-American Hotel built by Ellsworth Milton Statler A freelance journalist writing for Wikinews has obtained the only known reproduction photo of the hotel [pictured at the top]. The hotel stood on the northeast corner of Elmwood and Forest Avenues in Buffalo, had 2,100 sleeping rooms and accommodations for 5,000. At the time, the Statler was the largest hotel [based on the number of rooms] ever constructed. It was also the largest temporary hotel. It was three stories high, plastered on the inside, made mostly of wood and was covered with ornamental staff on the outside, which made it semi-fireproof. Every room was an outside room and was well lighted and ventilated. It was located within one block of the exposition’s main entrance.

The Statler was built for only one thing, the exposition. Work began in 1900 and finished just before the beginning of the exposition. When the exposition ended in November, the hotel was taken down.

Maps from 1894 show that there was no hotel, let alone any buildings or houses on the intersection. However; research did show that the homes 1119-1121 Elmwood, the buildings that would be demolished to build the Elmwood Village Hotel, were built sometime before 1915 but were not on the intersection prior to 1902.

Based on research conducted at the Buffalo Historical Society, it was concluded that between the years of 1890 and 1902, no other major hotel existed in the area. In fact, research had shown that almost every hotel built in the area, existed only during the time of the exposition.

Research also indicated a hotel or a rooming house at 1089 Elmwood around 1901-1903. The only known name of the hotel was the John C. Hill Hotel. The hotel was in the house now called the Atwater House. The house was the first house to be built on the east side of the block.

The Atwater House is currently vacant and owner Pano Georgiadis wants to demolish it to expand his restaurant. The house was built by 1894 and the original owner and builder of the house is currently unknown. Its earliest known occupant was Edward Atwater who in 1862 founded the oil refinery company of Atwater & Hawes in Buffalo. The site of this company was recently uncovered in the Canal District during an archeological dig.

At the moment, current research does not show any connection between the two men.

The exposition was a commercial failure and what profit Statler did make on the hotel, went to build another temporary hotel for the 1904 St. Louis Exhibition. That hotel was successful and the profit made from it was used to build the first permanent Statler Hotel at 107 Delaware Avenue in Buffalo. The hotel is no longer in operation, but small offices are currently operating in parts of the building.

Saturday, June 23, 2007

Belgium’s French-speaking Walloon region has officially recognised 43 mosques, thus giving Islam the same rights as accorded to other religions in the region. They will be permitted to build minarets on their mosques, and Imams will be added to the government payroll, as is the case – for example – with Catholic priests.

Moves are afoot to apply for official recognition of a number of mosques in the other two main regions of Belgium: Brussels, and Flemish-speaking Flanders.

Most of the immigrant population in Belgium are Muslims, but until now the mosques were not yet officially recognised. The traditional faith in Belgium is Roman Catholicism. Other minor faiths are Protestant Christianity, Orthodox Christianity, and Judaism.

Buddhists also recently applied for official recognition as a religion in Belgium.

Sunday, August 21, 2005

A robotic system at Stanford Medical Center was used to perform a laparoscopic gastric bypass surgery successfully with a theoretically similar rate of complications to that seen in standard operations. However, as there were only 10 people in the experimental group (and another 10 in the control group), this is not a statistically significant sample.

If this surgical procedure is as successful in large-scale studies, it may lead the way for the use of robotic surgery in even more delicate procedures, such as heart surgery. Note that this is not a fully automated system, as a human doctor controls the operation via remote control. Laparoscopic gastric bypass surgery is a treatment for obesity.

There were concerns that doctors, in the future, might only be trained in the remote control procedure. Ronald G. Latimer, M.D., of Santa Barbara, CA, warned “The fact that surgeons may have to open the patient or might actually need to revert to standard laparoscopic techniques demands that this basic training be a requirement before a robot is purchased. Robots do malfunction, so a backup system is imperative. We should not be seduced to buy this instrument to train surgeons if they are not able to do the primary operations themselves.”

There are precedents for just such a problem occurring. A previous “new technology”, the electrocardiogram (ECG), has lead to a lack of basic education on the older technology, the stethoscope. As a result, many heart conditions now go undiagnosed, especially in children and others who rarely undergo an ECG procedure.